Endocrine Abstracts

Introduction: Metabolic syndrome (MetS) is a group of metabolic abnormalities where insulin resistance (IR) plays a major role. Previous studies have shown that thyroid volume and nodule prevalence were increased in patients with IR. The aim of our study is to evaluate MetS and its components in patients with benign and malignant nodular thyroid disease (NTD).Methods: A total of 800 patients (430 euthyroid benign and 370 euthyroid malignant NTD) followed...

BackgroundObesity is an increasing public health problem all around the world. It plays role in the pathogenesis of many diseases, especially diabetes, hypertension, hyperlipidemia, cardiovascular diseases and cancer. The prevalence of weight-loss surgery is increasing as a result of developments of surgical techniques. In parallel with these developments, more patients admit for weight-loss surgery. Pharmacotherapy is one of the most important component...

Aim: There is a lack of studies in the literature evaluating the relationship between oral health, oral mucosal lesions, dental hygiene status, and disease prognosis in acromegaly patients. Our study aimed to assess oral mucosa in acromegaly patients, predict dental problems that may develop, correlate oral lesions and mucosal status with patients’ IGF-1 levels, investigate the relationship with the treatment method used, and evaluate the oral mucosal damage caused by con...

Aim: Hashimoto Thyroiditis (HT); is the most common form of hpothyroidism in iodine-sufficient regions. Both genes and and environmental factors are involved in the immunopathological process of HT. Our aim in this study is to determine the prevalence of Thyrothropin Receptor (TSHR), Cytotoxic T Lypmhocyte Antigen-4 (CTLA-4) and Interleukin-1 Receptor Antagonist (IL-1RN) gene polymorphisms associated with HT in Turkish population and the relationship of genotype characteristic...

Introduction: Primary hyperparathyroidism (PHPT) clinic occurs when the parathyroid glands secrete excess parathormone (PTH) due to hyperplasia, adenomatous or carcinomatous change. In the pathogenesis of the disease, dysregulation has been observed in extracellular signal-regulated 1/2 (ERK 1/2) pathways from the mitogen activated protein kinase (MAPK) family, c-Jun N-terminal kinase (JNK) pathways, and phosphatidylinositol-3 kinase (PI3K) pathways. Progranulin (PGRN) is a gl...

Introduction and Aim: In our study, the frequency of exocrine pancreatic insufficiency, and its relationship with the duration of diabetes and the level of glycemic control and other complications of diabetes were investigated in patients with diabetes mellitus.Materials and Methods: This paper was supported by Manisa Celal Bayar University Scientific Research Projects Coordination Unit, Project Number 2021-086. A total of 249 diabetic patients, 21 with ...

Aim: Currently, imaging tools are increasing the frequency of thyroid nodules to 50%, and thyroid cancer risk is 7-15%. The most cost-effective, accurate diagnosis method is fine-needle aspiration biopsy (FNAB). However, non-diagnostic (ND) results can delay diagnosis, cause different procedures, raise costs, and distress patients. In addition, FNAB sample adequacy is affected by advanced age, nodule size (<5-10mm), cystic dominating nodules, macrocalcification, and hypo-e...

Aim: Thyroid hormones have many effects on the cardiovascular system. May studies have showed that apparent or subclinical hypothyroidism increase the risk of hypertension hyperlipidemia and so lead to atherosclerosis susceptibility. This risk can be reduced by treatment. But, studies on the relationship between thyroid function tests and cardiovascular risk in euthyroid subjects are contradictory. This study was designed to investigate the effect of TSH, free T3, f...

Adrenal lymphangioma is a rare benign tumors of the adrenal gland. Because of the increased use of imaging methods in recent times, the diagnosis is usually made incidentally. It is usually due to malformation between the lymphatic and the venous system. Those with small indiameters are generally asymptomatic and can be evacuated by needlea spiration. However, surgery is recommended for cysts over 6 cm in diameter due to risk of infection, bleeding, compression of neighboring ...

Introduction: Current studies suggest that fractalkine (FKN) could be a pathogenic factor associated with adipocyte dysfunction and type 2 diabetes (T2DM) and have shown that FKN serum levels are increased in T2DM patients. The aim of this study was determined as evaluating the change of FKN levels that will occur with oral glucose tolerance test (OGTT).Methods: The study included 67 patients to whom OGTT was applied. The patients with the history of dia...